Jul 29, 2008

Auditory and Spatial Navigation Imagery in Brain-Computer Interface using Optimized Wavelets

Auditory and Spatial Navigation Imagery in Brain-Computer Interface using Optimized Wavelets.

J Neurosci Methods. 2008 Jul 6;

Authors: Cabrera AF, Dremstrup K

Features extracted with optimized wavelets were compared with standard methods for a Brain-Computer Interface driven by non-motor imagery tasks. Two non-motor imagery tasks were used, Auditory Imagery of a familiar tune and Spatial Navigation Imagery through a familiar environment. The aims of this study were to evaluate which method extracts features that could be best differentiated and determine which channels are best suited for classification. EEG activity from 18 electrodes over the temporal and parietal lobes of nineteen healthy subjects was recorded. The features used were autoregressive and reflection coefficients extracted using autoregressive modeling with several model orders and marginals of the wavelet spaces generated by the Discrete Wavelet Transform (DWT). An optimization algorithm with 4 and 6 taps filters and mother wavelets from the Daubechies family were used. The classification was performed for each single channel and for all possible combination of two channels using a Bayesian Classifier. The best classification results were found using the marginals of the Optimized DWT spaces for filters with 6 taps in a 2 channels classification basis. Classification using 2 channels was found to be significantly better than using 1 channel (p<<0.01). The marginals of the optimized DWT using 6 taps filters showed to be significantly better than the marginals of the Daubechies family and autoregressive coefficients. The influence of the combination of number of channels and feature extraction method over the classification results was not significant (p=0.97).

Jul 16, 2008

Einstein's Brain Game

Via MobileGames 

The Walt Disney Internet Group has released the "Einstein's Brain Game".


The game proposes 20 brain training exercises covering Einstein’s theories of relativity and ideas about the solar system. It features 4 categories - maths, memory, logic and visual coordination, as well as a bonus Sudoku puzzle game, to give the brain a thorough work-out.

 

Nov 25, 2007

Cognitive enhancement on BMA

 
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The British Medical Association has just released a report on the ethical implications of using medical technology to enhance cognitive function and optimise the brain

Sep 09, 2007

MindFit

Via SharpBrains 

MindFit is a software-based assessment and training program for 14 cognitive skills important for healthy aging. The software is recommended for people over 50 who want a novel and varied mental workout. The program has 21 exercises that train 14 cognitive skills.

MindFit was recently launched by Susan Greenfield, one of Britain's best-known neuroscientists

Link to BBC report

Mar 19, 2007

MindFit Clinical Trial Results Announced

 
NEW YORK and YOQNEAM, Israel, March 16 /PRNewswire/
 
For the first time, a double-blind clinical trial has shown that computer-based training improves the cognitive functions of the 50-plus crowd.

Against conventional wisdom, the computer training in MindFit(tm) cognitive skill assessment and training software, created by CogniFit, Ltd. http://www.cognifit.com), was found to improve short-term memory, spatial relations and attention focus--all skills used in driving and other daily activities that maintain our independence as we age.

The trial was conducted at the Tel-Aviv Sourasky Medical Center of Tel-Aviv University in Israel, where researchers are taking a leading role in the study of age-related disorders. During the two-year clinical trial, doctors conducted a prospective, randomized, double-blind study with active comparators of 121 self-referred volunteer participants age 50 and older. Each study participant was randomly assigned to spend 30 minutes, three times a week during the course of three months at home, using either MindFit or sophisticated computer games.

While all study participants benefited from the use of computer games, MindFit users experienced greater improvement in the cognitive domains of spatial short term memory, visuo-spatial learning and focused attention. Additionally, MindFit users in the study with lower baseline cognitive performance gained more than those with normal cognition, showing the potential therapeutic effect of home-based computer training software in those already suffering the effects of aging or more serious diseases.


"These research findings show unequivocally that MindFit, which requires no previous computer experience of users, keeps minds sharper than other computer games and software can," said Prof. Shlomo Breznitz, Ph.D., founder and president of CogniFit. "In fact, the same cognitive domains that MindFit keeps sharp are also central in most daily activities-including driving-that enable aging independently."

Breznitz continued, "These findings support CogniFit's belief that if you exercise your brain just as you do your muscles, you can build the speed and accuracy of your mental functions, significantly. 'Working out' with MindFit three times a week from the comfort of your home will yield similar results for your brain as exercising at the gym with that same frequency does for your muscles."

"We are additionally encouraged by the implications of our findings for those already below baseline in cognitive performance," said Nir Giladi, M.D., principal investigator, senior neurologist for the Department of Neurology for Tel-Aviv University's Tel-Aviv Sourasky Medical Center and faculty member in Tel-Aviv University's Sackler School of Medicine. "In the future, we may research MindFit's effect on Alzheimer's disease and forms of dementia."

MindFit software helps to assess and build overall cognitive skills for baby boomers, seniors and people of all ages. In other research studies, MindFit has helped users to improve their short-term memory by 18 percent. The comprehensive cognitive training program assesses, trains and enhances cognitive skills--including memory, focus, learning and concentration and safeguards overall cognitive vitality, an overall concept patented by CogniFit.

After an initial assessment session, users are encouraged to train with the software on their home PCs three times a week for 20 minutes a day. Then, MindFit provides fun, individualized training to match users' unique cognitive skill sets, changing exercises and levels to suit each individual's unique needs. No other cognitive assessment or training software product on the market has that personally tailoring technology.

Feb 25, 2007

TANGO: The Next Generation of Assitive Communication Devices

tango.jpg

 

Via Medgadget 

 

A company called Blink Twice is developing a speech-generating device that promises to improve the way differently-abled children communicate with their world:

 

The tango! is an amazing communication aid that accomplishes all the amazing things you've seen in the emulation. It contains phrases, words, and spelling, all in easier-to-understand, digitally enhanced or synthesized voices. In a snap, it lets you create photo albums, do voice-morphing, and change icons using photos.

The tango! is the first speech-generating device to bring the power of mass communications and consumer electronics to the world of AAC. It combines a broad array of communication methods, such as an intuitive language hierarchy, ingenious new icons, and easy-to-access pop-ups, with the vast power of consumer electronics - like a built-in camera and voice morphing, so individuals can better match their specific communication needs with the best features to achieve them.


Dec 28, 2006

The state of mental-gymnastic

Via the BrainBlog

The New York Times has a front-page article concerning the current state of mental-gymnastic services. From the article:

Science is not sure yet, but across the country, brain health programs are springing up, offering the possibility of a cognitive fountain of youth.

From “brain gyms” on the Internet to “brain-healthy” foods and activities at assisted living centers, the programs are aimed at baby boomers anxious about entering their golden years and at their parents trying to stave off memory loss or dementia.

“This is going to be one of the hottest topics in the next five years — it’s going to be huge,” said Nancy Ceridwyn, co-director of special projects for the American Society on Aging. “The challenge we have is it’s going to be a lot like the anti-aging industry: how much science is there behind this?”

...

Read the full article

Dec 20, 2006

Top 25 Questions About Brain Fitness

Elkhonon Goldberg, Alvaro Fernandez and Caroline Latham (Sharpbrains) have written Brain Fitness for Sharp Brains: Your New New Year Resolution, an introductory guide to the concept, science, and practice of brain fitness

A free copy of the report can be ordered here 

Positive effects of cognitive training on daily function and cognitive abilities

Via Smart Mobs 

The Journal of the American Medical Association (JAMA) has published a study entitled "Long-term Effects of Cognitive Training on Everyday Functional Outcomes in Older Adults" that shows the positive effects of cognitive training on daily function and cognitive abilities.

Authors: Sherry L. Willis, PhD; Sharon L. Tennstedt, PhD; Michael Marsiske, PhD; Karlene Ball, PhD; Jeffrey Elias, PhD; Kathy Mann Koepke, PhD; John N. Morris, PhD; George W. Rebok, PhD; Frederick W. Unverzagt, PhD; Anne M. Stoddard, ScD; Elizabeth Wright, PhD.

JAMA. 2006;296:2805-2814.

Context. Cognitive training has been shown to improve cognitive abilities in older adults but the effects of cognitive training on everyday function have not been demonstrated.  Objective. To determine the effects of cognitive training on daily function and durability of training on cognitive abilities. Design, Setting, and Participants. Five-year follow-up of a randomized controlled single-blind trial with 4 treatment groups. A volunteer sample of 2832 persons (mean age, 73.6 years; 26% black), living independently in 6 US cities, was recruited from senior housing, community centers, and hospitals and clinics. The study was conducted between April 1998 and December 2004. Five-year follow-up was completed in 67% of the sample. Interventions. Ten-session training for memory (verbal episodic memory), reasoning (inductive reasoning), or speed of processing (visual search and identification); 4-session booster training at 11 and 35 months after training in a random sample of those who completed training. Main Outcome Measures. Self-reported and performance-based measures of daily function and cognitive abilities. Results. The reasoning group reported significantly less difficulty in the instrumental activities of daily living (IADL) than the control group (effect size, 0.29; 99% confidence interval [CI], 0.03-0.55). Neither speed of processing training (effect size, 0.26; 99% CI, –0.002 to 0.51) nor memory training (effect size, 0.20; 99% CI, –0.06 to 0.46) had a significant effect on IADL. The booster training for the speed of processing group, but not for the other 2 groups, showed a significant effect on the performance-based functional measure of everyday speed of processing (effect size, 0.30; 99% CI, 0.08-0.52). No booster effects were seen for any of the groups for everyday problem-solving or self-reported difficulty in IADL. Each intervention maintained effects on its specific targeted cognitive ability through 5 years (memory: effect size, 0.23 [99% CI, 0.11-0.35]; reasoning: effect size, 0.26 [99% CI, 0.17-0.35]; speed of processing: effect size, 0.76 [99% CI, 0.62-0.90]). Booster training produced additional improvement with the reasoning intervention for reasoning performance (effect size, 0.28; 99% CI, 0.12-0.43) and the speed of processing intervention for speed of processing performance (effect size, 0.85; 99% CI, 0.61-1.09). Conclusions. Reasoning training resulted in less functional decline in self-reported IADL. Compared with the control group, cognitive training resulted in improved cognitive abilities specific to the abilities trained that continued 5 years after the initiation of the intervention.

Link to full-text article

Link to Washington Post report about the study

Dec 15, 2006

Neuroenhancement technology: an ethical analysis

Via IEET

Belgian government funds researcher to study neuroenhancement:

‘Neuroenhancement technology: an ethical analysis and study of the conditions for research and clinical trials.’

A project funded by the Flemish Fund for Scientific Research (G.0048.07) 01/01/2007-31/12/2010.

Aim and objectives:

The emergence of new treatments which have the capacity to profoundly alter or influence mood and cognition is considered by some as one of the most promising as well as most challenging developments of the 21st century within the life sciences (Wolp, 2002). Aside of other socially relevant aspects of current neuroscience (e.g. ‘brain reading’ ) and its technological tools (e.g. fMRI, TMS, PET), it is in particular the discussions regarding ethical and social implications of neuroenhancement technology which are giving rise to the gradual development of ‘neuroethics’. Some of the most pertinent concerns which shape this emerging domain include questions as to how this technology relates to the general goals of medicine and what the conditions for research and clinical trials should be. While the need for a thorough exploraiton of the social and ethical implications of enhancement technology is generally well acknowledged, scarce attention has gone out to the question if and under what conditions such research should be supported.

The aims of the research proposal are the following:

(1) to provide an overview of the current developments and results within neuroenhancement technology;

(2) to obtain thorough insight in the academic, social and policy debates surrounding these developments;

(3) to conduct a conceptual analysis of the conflict between ‘normal’, ‘healthy’ mental functioning and ‘enhanced’ functioning, both in terms of strictly medical as well as medical ethical standards;

(4) to conduct a comparative, medical ethical study of the conditions for acceptance of this and other forms of enhancement technology; and

(5) to apply the results obtained from the analyses to the current context of neuroenhancement technology.

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