Oct 06, 2014

Bionic Vision Australia’s Bionic Eye Gives New Sight to People Blinded by Retinitis Pigmentosa

Via Medgadget

Bionic Vision Australia, a collaboration between of researchers working on a bionic eye, has announced that its prototype implant has completed a two year trial in patients with advanced retinitis pigmentosa. Three patients with profound vision loss received 24-channel suprachoroidal electrode implants that caused no noticeable serious side effects. Moreover, though this was not formally part of the study, the patients were able to see more light and able to distinguish shapes that were invisible to them prior to implantation. The newly gained vision allowed them to improve how they navigated around objects and how well they were able to spot items on a tabletop.

The next step is to try out the latest 44-channel device in a clinical trial slated for next year and then move on to a 98-channel system that is currently in development.

This study is critically important to the continuation of our research efforts and the results exceeded all our expectations,” Professor Mark Hargreaves, Chair of the BVA board, said in a statement. “We have demonstrated clearly that our suprachoroidal implants are safe to insert surgically and cause no adverse events once in place. Significantly, we have also been able to observe that our device prototype was able to evoke meaningful visual perception in patients with profound visual loss.”

Here’s one of the study participants using the bionic eye:

First direct brain-to-brain communication between human subjects

Via KurzweilAI.net

An international team of neuroscientists and robotics engineers have demonstrated the first direct remote brain-to-brain communication between two humans located 5,000 miles away from each other and communicating via the Internet, as reported in a paper recently published in PLOS ONE (open access).

Emitter and receiver subjects with non-invasive devices supporting, respectively, a brain-computer interface (BCI), based on EEG changes, driven by motor imagery (left) and a computer-brain interface (CBI) based on the reception of phosphenes elicited by neuro-navigated TMS (right) (credit: Carles Grau et al./PLoS ONE)

In India, researchers encoded two words (“hola” and “ciao”) as binary strings and presented them as a series of cues on a computer monitor. They recorded the subject’s EEG signals as the subject was instructed to think about moving his feet (binary 0) or hands (binary 1). They then sent the recorded series of binary values in an email message to researchers in France, 5,000 miles away.

There, the binary strings were converted into a series of transcranial magnetic stimulation (TMS) pulses applied to a hotspot location in the right visual occipital cortex that either produced a phosphene (perceived flash of light) or not.

“We wanted to find out if one could communicate directly between two people by reading out the brain activity from one person and injecting brain activity into the second person, and do so across great physical distances by leveraging existing communication pathways,” explains coauthor Alvaro Pascual-Leone, MD, PhD, Director of the Berenson-Allen Center for Noninvasive Brain Stimulation at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Neurology at Harvard Medical School.

 A team of researchers from Starlab Barcelona, Spain and Axilum Robotics, Strasbourg, France conducted the experiment. A second similar experiment was conducted between individuals in Spain and France.

“We believe these experiments represent an important first step in exploring the feasibility of complementing or bypassing traditional language-based or other motor/PNS mediated means in interpersonal communication,” the researchers say in the paper.

“Although certainly limited in nature (e.g., the bit rates achieved in our experiments were modest even by current BCI (brain-computer interface) standards, mostly due to the dynamics of the precise CBI (computer-brain interface) implementation, these initial results suggest new research directions, including the non-invasive direct transmission of emotions and feelings or the possibility of sense synthesis in humans — that is, the direct interface of arbitrary sensors with the human brain using brain stimulation, as previously demonstrated in animals with invasive methods.

Brain-to-brain (B2B) communication system overview. On the left, the BCI subsystem is shown schematically, including electrodes over the motor cortex and the EEG amplifier/transmitter wireless box in the cap. Motor imagery of the feet codes the bit value 0, of the hands codes bit value 1. On the right, the CBI system is illustrated, highlighting the role of coil orientation for encoding the two bit values. Communication between the BCI and CBI components is mediated by the Internet. (Credit: Carles Grau et al./PLoS ONE)

“The proposed technology could be extended to support a bi-directional dialogue between two or more mind/brains (namely, by the integration of EEG and TMS systems in each subject). In addition, we speculate that future research could explore the use of closed mind-loops in which information associated to voluntary activity from a brain area or network is captured and, after adequate external processing, used to control other brain elements in the same subject. This approach could lead to conscious synthetically mediated modulation of phenomena best detected subjectively by the subject, including emotions, pain and psychotic, depressive or obsessive-compulsive thoughts.

“Finally, we anticipate that computers in the not-so-distant future will interact directly with the human brain in a fluent manner, supporting both computer- and brain-to-brain communication routinely. The widespread use of human brain-to-brain technologically mediated communication will create novel possibilities for human interrelation with broad social implications that will require new ethical and legislative responses.”

This work was partly supported by the EU FP7 FET Open HIVE project, the Starlab Kolmogorov project, and the Neurology Department of the Hospital de Bellvitge.

 

Aug 03, 2014

Detecting awareness in patients with disorders of consciousness using a hybrid brain-computer interface

Detecting awareness in patients with disorders of consciousness using a hybrid brain-computer interface.

J Neural Eng. 2014 Aug 1;11(5):056007

Authors: Pan J, Xie Q, He Y, Wang F, Di H, Laureys S, Yu R, Li Y

Abstract. Objective. The bedside detection of potential awareness in patients with disorders of consciousness (DOC) currently relies only on behavioral observations and tests; however, the misdiagnosis rates in this patient group are historically relatively high. In this study, we proposed a visual hybrid brain-computer interface (BCI) combining P300 and steady-state evoked potential (SSVEP) responses to detect awareness in severely brain injured patients. Approach. Four healthy subjects, seven DOC patients who were in a vegetative state (VS, n = 4) or minimally conscious state (MCS, n = 3), and one locked-in syndrome (LIS) patient attempted a command-following experiment. In each experimental trial, two photos were presented to each patient; one was the patient's own photo, and the other photo was unfamiliar. The patients were instructed to focus on their own or the unfamiliar photos. The BCI system determined which photo the patient focused on with both P300 and SSVEP detections. Main results. Four healthy subjects, one of the 4 VS, one of the 3 MCS, and the LIS patient were able to selectively attend to their own or the unfamiliar photos (classification accuracy, 66-100%). Two additional patients (one VS and one MCS) failed to attend the unfamiliar photo (50-52%) but achieved significant accuracies for their own photo (64-68%). All other patients failed to show any significant response to commands (46-55%). Significance. Through the hybrid BCI system, command following was detected in four healthy subjects, two of 7 DOC patients, and one LIS patient. We suggest that the hybrid BCI system could be used as a supportive bedside tool to detect awareness in patients with DOC.

Apr 15, 2014

Brain-computer interfaces: a powerful tool for scientific inquiry

Brain-computer interfaces: a powerful tool for scientific inquiry.

Curr Opin Neurobiol. 2014 Apr;25C:70-75

Authors: Wander JD, Rao RP

Abstract. Brain-computer interfaces (BCIs) are devices that record from the nervous system, provide input directly to the nervous system, or do both. Sensory BCIs such as cochlear implants have already had notable clinical success and motor BCIs have shown great promise for helping patients with severe motor deficits. Clinical and engineering outcomes aside, BCIs can also be tremendously powerful tools for scientific inquiry into the workings of the nervous system. They allow researchers to inject and record information at various stages of the system, permitting investigation of the brain in vivo and facilitating the reverse engineering of brain function. Most notably, BCIs are emerging as a novel experimental tool for investigating the tremendous adaptive capacity of the nervous system.

A Hybrid Brain Computer Interface System Based on the Neurophysiological Protocol and Brain-actuated Switch for Wheelchair Control

A Hybrid Brain Computer Interface System Based on the Neurophysiological Protocol and Brain-actuated Switch for Wheelchair Control.

J Neurosci Methods. 2014 Apr 5;

Authors: Cao L, Li J, Ji H, Jiang C

BACKGROUND: Brain Computer Interfaces (BCIs) are developed to translate brain waves into machine instructions for external devices control. Recently, hybrid BCI systems are proposed for the multi-degree control of a real wheelchair to improve the systematical efficiency of traditional BCIs. However, it is difficult for existing hybrid BCIs to implement the multi-dimensional control in one command cycle.
NEW METHOD: This paper proposes a novel hybrid BCI system that combines motor imagery (MI)-based bio-signals and steady-state visual evoked potentials (SSVEPs) to control the speed and direction of a real wheelchair synchronously. Furthermore, a hybrid modalities-based switch is firstly designed to turn on/off the control system of the wheelchair.
RESULTS: Two experiments were performed to assess the proposed BCI system. One was implemented for training and the other one conducted a wheelchair control task in the real environment. All subjects completed these tasks successfully and no collisions occurred in the real wheelchair control experiment.
COMPARISON WITH EXISTING METHOD(S): The protocol of our BCI gave much more control commands than those of previous MI and SSVEP-based BCIs. Comparing with other BCI wheelchair systems, the superiority reflected by the index of path length optimality ratio validated the high efficiency of our control strategy.
CONCLUSIONS: The results validated the efficiency of our hybrid BCI system to control the direction and speed of a real wheelchair as well as the reliability of hybrid signals-based switch control.

Mar 02, 2014

3D Thought controlled environment via Interaxon

In this demo video, artist Alex McLeod shows an environment he designed for Interaxon to use at CES in 2011 interaxon.ca/CES#.

The glasses display the scene in 3D and attaches sensors read users brain-states which control elements of the scene.

3D Thought controlled environment via Interaxon from Alex McLeod on Vimeo.

Dec 24, 2013

Speaking and cognitive distractions during EEG-based brain control of a virtual neuroprosthesis-arm

Speaking and cognitive distractions during EEG-based brain control of a virtual neuroprosthesis-arm.

J Neuroeng Rehabil. 2013 Dec 21;10(1):116

Authors: Foldes ST, Taylor DM

BACKGROUND: Brain-computer interface (BCI) systems have been developed to provide paralyzed individuals the ability to command the movements of an assistive device using only their brain activity. BCI systems are typically tested in a controlled laboratory environment were the user is focused solely on the brain-control task. However, for practical use in everyday life people must be able to use their brain-controlled device while mentally engaged with the cognitive responsibilities of daily activities and while compensating for any inherent dynamics of the device itself. BCIs that use electroencephalography (EEG) for movement control are often assumed to require significant mental effort, thus preventing users from thinking about anything else while using their BCI. This study tested the impact of cognitive load as well as speaking on the ability to use an EEG-based BCI. FINDINGS: Six participants controlled the two-dimensional (2D) movements of a simulated neuroprosthesis-arm under three different levels of cognitive distraction. The two higher cognitive load conditions also required simultaneously speaking during BCI use. On average, movement performance declined during higher levels of cognitive distraction, but only by a limited amount. Movement completion time increased by 7.2%, the percentage of targets successfully acquired declined by 11%, and path efficiency declined by 8.6%. Only the decline in percentage of targets acquired and path efficiency were statistically significant (p < 0.05). CONCLUSION: People who have relatively good movement control of an EEG-based BCI may be able to speak and perform other cognitively engaging activities with only a minor drop in BCI-control performance.

Dec 08, 2013

How to use mind-controlled robots in manufacturing, medicine

via KurzweilAI

University at Buffalo researchers are developing brain-computer interface (BCI) devices to mentally control robots.

“The technology has practical applications that we’re only beginning to explore,” said Thenkurussi “Kesh” Kesavadas, PhD, UB professor of mechanical and aerospace engineering and director of UB’s Virtual Reality Laboratory. “For example, it could help paraplegic patients to control assistive devices, or it could help factory workers perform advanced manufacturing tasks.”

Most BCI research has involved expensive, invasive BCI devices that are inserted into the brain, and used mostly to help disabled people.

UB research relies on a relatively inexpensive ($750), non-invasive external device (Emotiv EPOC). It reads EEG brain activity with 14 sensors and transmits the signal wirelessly to a computer, which then sends signals to the robot to control its movements.

Kesavadas recently demonstrated the technology with Pramod Chembrammel, a doctoral student in his lab.  Chembrammel trained with the instrument for a few days, then used the device to control a robotic arm.

He used the arm to insert a wood peg into a hole and rotate the peg. “It was incredible to see the robot respond to my thoughts,” Chembrammel said. “It wasn’t even that difficult to learn how to use the device.”

The video (below) shows that a simple set of instructions can be combined to execute more complex robotic actions, Kesavadas said. Such robots could be used by factory workers to perform hands-free assembly of products, or carry out tasks like drilling or welding.

The potential advantage, Kesavadas said, is that BCI-controlled devices could reduce the tedium of performing repetitious tasks and improve worker safety and productivity. The devices can also leverage the worker’s decision-making skills, such as identifying a faulty part in an automated assembly line.

Nov 29, 2013

Real-time Neurofeedback Using Functional MRI Could Improve Down-Regulation of Amygdala Activity During Emotional Stimulation

Real-time Neurofeedback Using Functional MRI Could Improve Down-Regulation of Amygdala Activity During Emotional Stimulation: A Proof-of-Concept Study.

Brain Topogr. 2013 Nov 16;

Authors: Brühl AB, Scherpiet S, Sulzer J, Stämpfli P, Seifritz E, Herwig U

Abstract. The amygdala is a central target of emotion regulation. It is overactive and dysregulated in affective and anxiety disorders and amygdala activity normalizes with successful therapy of the symptoms. However, a considerable percentage of patients do not reach remission within acceptable duration of treatment. The amygdala could therefore represent a promising target for real-time functional magnetic resonance imaging (rtfMRI) neurofeedback. rtfMRI neurofeedback directly improves the voluntary regulation of localized brain activity. At present, most rtfMRI neurofeedback studies have trained participants to increase activity of a target, i.e. up-regulation. However, in the case of the amygdala, down-regulation is supposedly more clinically relevant. Therefore, we developed a task that trained participants to down-regulate activity of the right amygdala while being confronted with amygdala stimulation, i.e. negative emotional faces. The activity in the functionally-defined region was used as online visual feedback in six healthy subjects instructed to minimize this signal using reality checking as emotion regulation strategy. Over a period of four training sessions, participants significantly increased down-regulation of the right amygdala compared to a passive viewing condition to control for habilitation effects. This result supports the concept of using rtfMRI neurofeedback training to control brain activity during relevant stimulation, specifically in the case of emotion, and has implications towards clinical treatment of emotional disorders.

Nov 28, 2013

Effect of mindfulness meditation on brain-computer interface performance

Effect of mindfulness meditation on brain-computer interface performance.

Conscious Cogn. 2013 Nov 22;23C:12-21

Authors: Tan LF, Dienes Z, Jansari A, Goh SY

Abstract. Electroencephalogram based Brain-Computer Interfaces (BCIs) enable stroke and motor neuron disease patients to communicate and control devices. Mindfulness meditation has been claimed to enhance metacognitive regulation. The current study explores whether mindfulness meditation training can thus improve the performance of BCI users. To eliminate the possibility of expectation of improvement influencing the results, we introduced a music training condition. A norming study found that both meditation and music interventions elicited clear expectations for improvement on the BCI task, with the strength of expectation being closely matched. In the main 12week intervention study, seventy-six healthy volunteers were randomly assigned to three groups: a meditation training group; a music training group; and a no treatment control group. The mindfulness meditation training group obtained a significantly higher BCI accuracy compared to both the music training and no-treatment control groups after the intervention, indicating effects of meditation above and beyond expectancy effects.

Nov 16, 2013

Monkeys Control Avatar’s Arms Through Brain-Machine Interface

Via Medgadget

Researchers at Duke University have reported in journal Science Translational Medicine that they were able to train monkeys to control two virtual limbs through a brain-computer interface (BCI). The rhesus monkeys initially used joysticks to become comfortable moving the avatar’s arms, but later the brain-computer interfaces implanted on their brains were activated to allow the monkeys to drive the avatar using only their minds. Two years ago the same team was able to train monkeys to control one arm, but the complexity of controlling two arms required the development of a new algorithm for reading and filtering the signals. Moreover, the monkey brains themselves showed great adaptation to the training with the BCI, building new neural pathways to help improve how the monkeys moved the virtual arms. As the authors of the study note in the abstract, “These findings should help in the design of more sophisticated BMIs capable of enabling bimanual motor control in human patients.”

Here’s a video of one of the avatars being controlled to tap on the white balls:

Nov 03, 2013

Neurocam wearable camera reads your brainwaves and records what interests you

Via KurzweilAI.net

The neurocam is the world’s first wearable camera system that automatically records what interests you, based on brainwaves, DigInfo TV reports.

It consists of a headset with a brain-wave sensor and uses the iPhone’s camera to record a 5-second GIF animation. It could also be useful for life-logging.

The algorithm for quantifying brain waves was co-developed by Associate Professor Mitsukura at Keio University.

The project team plans to create an emotional interface.

Aug 07, 2013

Pupil responses allow communication in locked-in syndrome patients

Pupil responses allow communication in locked-in syndrome patients.

Josef Stoll et al., Current Biology, Volume 23, Issue 15, R647-R648, 5 August 2013

For patients with severe motor disabilities, a robust means of communication is a crucial factor for their well-being. We report here that pupil size measured by a bedside camera can be used to communicate with patients with locked-in syndrome. With the same protocol we demonstrate command-following for a patient in a minimally conscious state, suggesting its potential as a diagnostic tool for patients whose state of consciousness is in question. Importantly, neither training nor individual adjustment of our system’s decoding parameters were required for successful decoding of patients’ responses.

Paper full text PDF

dilated pupil Pupils Used to Communicate with People with Locked In Syndrome

Image credit: Flickr user Beth77

May 26, 2013

A Hybrid Brain-Computer Interface-Based Mail Client

A Hybrid Brain-Computer Interface-Based Mail Client.

Comput Math Methods Med. 2013;2013:750934

Authors: Yu T, Li Y, Long J, Li F

Abstract. Brain-computer interface-based communication plays an important role in brain-computer interface (BCI) applications; electronic mail is one of the most common communication tools. In this study, we propose a hybrid BCI-based mail client that implements electronic mail communication by means of real-time classification of multimodal features extracted from scalp electroencephalography (EEG). With this BCI mail client, users can receive, read, write, and attach files to their mail. Using a BCI mouse that utilizes hybrid brain signals, that is, motor imagery and P300 potential, the user can select and activate the function keys and links on the mail client graphical user interface (GUI). An adaptive P300 speller is employed for text input. The system has been tested with 6 subjects, and the experimental results validate the efficacy of the proposed method.

Mar 03, 2013

Brain-to-brain communication between rats achieved

From Duke Medicine News and Communications

Researchers at Duke University Medical Center in the US report in the February 28, 2013 issue of Scientific Reports the successful wiring together of sensory areas in the brains of two rats. The result of the experiment is that one rat will respond to the experiences to which the other is exposed.

Brain-to-brain interface with rats | Duke

The results of these projects suggest the future potential for linking multiple brains to form what the research team is calling an "organic computer," which could allow sharing of motor and sensory information among groups of animals.

"Our previous studies with brain-machine interfaces had convinced us that the rat brain was much more plastic than we had previously thought," said Miguel Nicolelis, M.D., PhD, lead author of the publication and professor of neurobiology at Duke University School of Medicine. "In those experiments, the rat brain was able to adapt easily to accept input from devices outside the body and even learn how to process invisible infrared light generated by an artificial sensor. So, the question we asked was, ‘if the brain could assimilate signals from artificial sensors, could it also assimilate information input from sensors from a different body?’"

To test this hypothesis, the researchers first trained pairs of rats to solve a simple problem: to press the correct lever when an indicator light above the lever switched on, which rewarded the rats with a sip of water. They next connected the two animals' brains via arrays of microelectrodes inserted into the area of the cortex that processes motor information.

One of the two rodents was designated as the "encoder" animal. This animal received a visual cue that showed it which lever to press in exchange for a water reward. Once this “encoder” rat pressed the right lever, a sample of its brain activity that coded its behavioral decision was translated into a pattern of electrical stimulation that was delivered directly into the brain of the second rat, known as the "decoder" animal.

The decoder rat had the same types of levers in its chamber, but it did not receive any visual cue indicating which lever it should press to obtain a reward. Therefore, to press the correct lever and receive the reward it craved, the decoder rat would have to rely on the cue transmitted from the encoder via the brain-to-brain interface.

The researchers then conducted trials to determine how well the decoder animal could decipher the brain input from the encoder rat to choose the correct lever. The decoder rat ultimately achieved a maximum success rate of about 70 percent, only slightly below the possible maximum success rate of 78 percent that the researchers had theorized was achievable based on success rates of sending signals directly to the decoder rat’s brain.

Importantly, the communication provided by this brain-to-brain interface was two-way. For instance, the encoder rat did not receive a full reward if the decoder rat made a wrong choice. The result of this peculiar contingency, said Nicolelis, led to the establishment of a "behavioral collaboration" between the pair of rats.

"We saw that when the decoder rat committed an error, the encoder basically changed both its brain function and behavior to make it easier for its partner to get it right," Nicolelis said. "The encoder improved the signal-to-noise ratio of its brain activity that represented the decision, so the signal became cleaner and easier to detect. And it made a quicker, cleaner decision to choose the correct lever to press. Invariably, when the encoder made those adaptations, the decoder got the right decision more often, so they both got a better reward."

In a second set of experiments, the researchers trained pairs of rats to distinguish between a narrow or wide opening using their whiskers. If the opening was narrow, they were taught to nose-poke a water port on the left side of the chamber to receive a reward; for a wide opening, they had to poke a port on the right side.

The researchers then divided the rats into encoders and decoders. The decoders were trained to associate stimulation pulses with the left reward poke as the correct choice, and an absence of pulses with the right reward poke as correct. During trials in which the encoder detected the opening width and transmitted the choice to the decoder, the decoder had a success rate of about 65 percent, significantly above chance.

To test the transmission limits of the brain-to-brain communication, the researchers placed an encoder rat in Brazil, at the Edmond and Lily Safra International Institute of Neuroscience of Natal (ELS-IINN), and transmitted its brain signals over the Internet to a decoder rat in Durham, N.C. They found that the two rats could still work together on the tactile discrimination task.

"So, even though the animals were on different continents, with the resulting noisy transmission and signal delays, they could still communicate," said Miguel Pais-Vieira, PhD, a postdoctoral fellow and first author of the study. "This tells us that it could be possible to create a workable, network of animal brains distributed in many different locations."

Nicolelis added, "These experiments demonstrated the ability to establish a sophisticated, direct communication linkage between rat brains, and that the decoder brain is working as a pattern-recognition device. So basically, we are creating an organic computer that solves a puzzle."

"But in this case, we are not inputting instructions, but rather only a signal that represents a decision made by the encoder, which is transmitted to the decoder’s brain which has to figure out how to solve the puzzle. So, we are creating a single central nervous system made up of two rat brains,” said Nicolelis.  He pointed out that, in theory, such a system is not limited to a pair of brains, but instead could include a network of brains, or “brain-net.” Researchers at Duke and at the ELS-IINN are now working on experiments to link multiple animals cooperatively to solve more complex behavioral tasks.

"We cannot predict what kinds of emergent properties would appear when animals begin interacting as part of a brain-net. In theory, you could imagine that a combination of brains could provide solutions that individual brains cannot achieve by themselves," continued Nicolelis. Such a connection might even mean that one animal would incorporate another's sense of "self," he said.

"In fact, our studies of the sensory cortex of the decoder rats in these experiments showed that the decoder's brain began to represent in its tactile cortex not only its own whiskers, but the encoder rat's whiskers, too. We detected cortical neurons that responded to both sets of whiskers, which means that the rat created a second representation of a second body on top of its own." Basic studies of such adaptations could lead to a new field that Nicolelis calls the "neurophysiology of social interaction."

Such complex experiments will be enabled by the laboratory's ability to record brain signals from almost 2,000 brain cells at once. The researchers hope to record the electrical activity produced simultaneously by 10-30,000 cortical neurons in the next five years.

Such massive brain recordings will enable more precise control of motor neuroprostheses—such as those being developed by the Walk Again Project—to restore motor control to paralyzed people, Nicolelis said.

More to explore:

Pais-Vieira, M., Lebedev, M., Kunicki, C., Wang, J. & Nicolelis, M. A. L. Sci. Rep. 3, 1319 (2013). PUBMED

Jul 14, 2012

Robot avatar body controlled by thought alone

Via: New Scientist

For the first time, a person lying in an fMRI machine has controlled a robot hundreds of kilometers away using thought alone.

"The ultimate goal is to create a surrogate, like in Avatar, although that’s a long way off yet,” says Abderrahmane Kheddar, director of the joint robotics laboratory at the National Institute of Advanced Industrial Science and Technology in Tsukuba, Japan.

Teleoperated robots, those that can be remotely controlled by a human, have been around for decades. Kheddar and his colleagues are going a step further. “True embodiment goes far beyond classical telepresence, by making you feel that the thing you are embodying is part of you,” says Kheddar. “This is the feeling we want to reach.”

To attempt this feat, researchers with the international Virtual Embodiment and Robotic Re-embodiment project used fMRI to scan the brain of university student Tirosh Shapira as he imagined moving different parts of his body. He attempted to direct a virtual avatar by thinking of moving his left or right hand or his legs.

The scanner works by measuring changes in blood flow to the brain’s primary motor cortex, and using this the team was able to create an algorithm that could distinguish between each thought of movement (see diagram). The commands were then sent via an internet connection to a small robot at the Béziers Technology Institute in France.

The set-up allowed Shapira to control the robot in near real time with his thoughts, while a camera on the robot’s head allowed him to see from the robot’s perspective. When he thought of moving his left or right hand, the robot moved 30 degrees to the left or right. Imagining moving his legs made the robot walk forward.

Read further at: http://www.newscientist.com/article/mg21528725.900-robot-avatar-body-controlled-by-thought-alone.html

Jul 05, 2012

A Real-Time fMRI-Based Spelling Device Immediately Enabling Robust Motor-Independent Communication

A Real-Time fMRI-Based Spelling Device Immediately Enabling Robust Motor-Independent Communication.

Curr Biol. 2012 Jun 27

Authors: Sorger B, Reithler J, Dahmen B, Goebel R

Human communication entirely depends on the functional integrity of the neuromuscular system. This is devastatingly illustrated in clinical conditions such as the so-called locked-in syndrome (LIS) [1], in which severely motor-disabled patients become incapable to communicate naturally-while being fully conscious and awake. For the last 20 years, research on motor-independent communication has focused on developing brain-computer interfaces (BCIs) implementing neuroelectric signals for communication (e.g., [2-7]), and BCIs based on electroencephalography (EEG) have already been applied successfully to concerned patients [8-11]. However, not all patients achieve proficiency in EEG-based BCI control [12]. Thus, more recently, hemodynamic brain signals have also been explored for BCI purposes [13-16]. Here, we introduce the first spelling device based on fMRI. By exploiting spatiotemporal characteristics of hemodynamic responses, evoked by performing differently timed mental imagery tasks, our novel letter encoding technique allows translating any freely chosen answer (letter-by-letter) into reliable and differentiable single-trial fMRI signals. Most importantly, automated letter decoding in real time enables back-and-forth communication within a single scanning session. Because the suggested spelling device requires only little effort and pretraining, it is immediately operational and possesses high potential for clinical applications, both in terms of diagnostics and establishing short-term communication with nonresponsive and severely motor-impaired patients.

May 07, 2012

CFP – Brain Computer Interfaces Grand Challenge 2012

brain-computer-interface-1.jpg

(From the CFP website)

Sensors, such as wireless EEG caps, that provide us with information about the brain activity are becoming available for use outside the medical domain. As in the case of physiological sensors information derived from these sensors can be used – as an information source for interpreting the user’s activity and intentions. For example, a user can use his or her brain activity to issue commands by using motor imagery. But this control-oriented interaction is unreliable and inefficient compared to other available interaction modalities. Moreover a user needs to behave as almost paralyzed (sit completely still) to generate artifact-free brain activity which can be recognized by the Brain-Computer Interface (BCI).

Of course BCI systems are improving in various ways; improved sensors, better recognition techniques, software that is more usable, natural, and context aware, hybridization with physiological sensors and other communication systems. New applications arise at the horizon and are explored, such as motor recovery and entertainment. Testing and validation with target users in home settings is becoming more common. These and other developments are making BCIs increasingly practical for conventional users (persons with severe motor disabilities) as well as non-disabled users. But despite this progress BCIs remain, as a control interface, quite limited in real world settings. BCIs are slow and unreliable, particularly over extended periods with target users. BCIs require expert assistance in many ways; a typical end user today needs help to identify, buy, setup, configure, maintain, repair and upgrade the BCI. User-centered design is underappreciated, with BCIs meeting the goals and abilities of the designer rather than user. Integration in the daily lives of people is just beginning. One of the reasons why this integration is problematic is due to view point of BCI as control device; mainly due to the origin of BCI as a control mechanism for severely physical disabled people.

In this challenge (organised within the framework of the Call for Challenges at ICMI 2012), we propose to change this view point and therefore consider BCI as an intelligent sensor, similar to a microphone or camera, which can be used in multimodal interaction. A typical example is the use of BCI in sonification of brain signals is the exposition Staalhemel created by Christoph de Boeck. Staalhemel is an interactive installation with 80 steel segments suspended over the visitor’s head as he walks through the space. Tiny hammers tap rhythmic patterns on the steel plates, activated by the brainwaves of the visitor who wears a portable BCI (EEG scanner). Thus, visitors are directly interacting with their surroundings, in this case a artistic installation.

The main challenges to research and develop BCIs as intelligent sensors include but are not limited to:

  • How could BCIs as intelligent sensors be integrated in multimodal HCI, HRI and HHI applications alongside other modes of input control?
  • What constitutes appropriate categories of adaptation (to challenge, to help, to promote positive emotion) in response to physiological data?
  • What are the added benefits of this approach with respect to user experience of HCI, HRI and HHI with respect to performance, safety and health?
  • How to present the state of the user in the context of HCI or HRI (representation to a machine) compared to HHI (representation to the self or another person)?
  • How to design systems that promote trust in the system and protect the privacy of the user?
  • What constitutes opportune support for BCI based intelligent sensor? In other words, how can the interface adapt to the user information such that the user feels supported rather than distracted?
  • What is the user experience of HCI, HRI and HHI enhanced through BCIs as intelligent sensors?
  • What are the ethical, legal and societal implications of such technologies? And how can we address these issues timely?

We solicit papers, demonstrators, videos or design descriptions of possible demonstrators that address the above challenges. Demonstrators and videos should be accompanied by a paper explaining the design. Descriptions of possible demonstrators can be presented through a poster.
Accepted papers will be included in the ICMI conference proceedings, which will be published by ACM as part of their series of International Conference Proceedings. As such the ICMI proceedings will have an ISBN number assigned to it and all papers will have a unique DOI and URL assigned to them. Moreover, all accepted papers will be included in the ACM digital library.

Important dates

Deadline for submission: June 15, 2012
Notification of acceptance: July 7, 2012
Final paper: August 15, 2102

Grand Challenge Website:
 

 

 

 

Mind-controlled robot allows a quadriplegic patient moving virtually in space

Researchers at Federal Institute of Technology in Lausanne, Switzerland (EPFL), have successfully demonstrated a robot controlled by the mind of a partially quadriplegic patient in a hospital 62 miles away. The EPFL brain-computer interface system does not require invasive neural implants in the brain, since it is based on a special EEG cap fitted with electrodes that record the patient’s neural signals. The task of the patient is to imagine moving his paralyzed fingers, and this input is than translated by the BCI system into command for the robot.

Apr 20, 2012

Mental workload during brain-computer interface training

Mental workload during brain-computer interface training.

Ergonomics. 2012 Apr 16;

Authors: Felton EA, Williams JC, Vanderheiden GC, Radwin RG

Abstract. It is not well understood how people perceive the difficulty of performing brain-computer interface (BCI) tasks, which specific aspects of mental workload contribute the most, and whether there is a difference in perceived workload between participants who are able-bodied and disabled. This study evaluated mental workload using the NASA Task Load Index (TLX), a multi-dimensional rating procedure with six subscales: Mental Demands, Physical Demands, Temporal Demands, Performance, Effort, and Frustration. Able-bodied and motor disabled participants completed the survey after performing EEG-based BCI Fitts' law target acquisition and phrase spelling tasks. The NASA-TLX scores were similar for able-bodied and disabled participants. For example, overall workload scores (range 0-100) for 1D horizontal tasks were 48.5 (SD = 17.7) and 46.6 (SD 10.3), respectively. The TLX can be used to inform the design of BCIs that will have greater usability by evaluating subjective workload between BCI tasks, participant groups, and control modalities. Practitioner Summary: Mental workload of brain-computer interfaces (BCI) can be evaluated with the NASA Task Load Index (TLX). The TLX is an effective tool for comparing subjective workload between BCI tasks, participant groups (able-bodied and disabled), and control modalities. The data can inform the design of BCIs that will have greater usability.

1 2 3 4 5 6 7 Next