Positive Technology Journal

Potential for new technologies in clinical practice.

Curr Opin Neurol. 2010 Oct 18;

Authors: Burridge JH, Hughes AM

PURPOSE OF REVIEW: Cost-effective neurorehabilitation is essential owing to financial constraints on healthcare resources. Technologies have the potential to contribute but without strong clinical evidence are unlikely to be widely reimbursed. This review presents evidence of new technologies since 2008 and identifies barriers to translation of technologies into clinical practice. RECENT FINDINGS: Technology has not been shown to be superior to intensively matched existing therapies. Research has been undertaken into the development and preliminary clinical testing of novel technologies including robotics, electrical stimulation, constraint-induced movement therapy, assistive orthoses, noninvasive brain stimulation, virtual reality and gaming devices. Translation of the research into clinical practice has been impeded by a lack of robust evidence of clinical effectiveness and usability. Underlying mechanisms associated with recovery are beginning to be explored, which may lead to more targeted interventions. Improvements in function have been demonstrated beyond the normal recovery period, but few trials demonstrate lasting effects. SUMMARY: Technologies, alone or combined, may offer a cost-effective way to deliver intensive neurorehabilitation therapy in clinical and community environments, and have the potential to empower patients to take more responsibility for their rehabilitation and continue with long-term exercise.

Neurocognitive systems related to real-world prospective memory.

PLoS One. 2010;5(10):

Authors: Kalpouzos G, Eriksson J, Sjölie D, Molin J, Nyberg L

BACKGROUND: Prospective memory (PM) denotes the ability to remember to perform actions in the future. It has been argued that standard laboratory paradigms fail to capture core aspects of PM. METHODOLOGY/PRINCIPAL FINDINGS: We combined functional MRI, virtual reality, eye-tracking and verbal reports to explore the dynamic allocation of neurocognitive processes during a naturalistic PM task where individuals performed errands in a realistic model of their residential town. Based on eye movement data and verbal reports, we modeled PM as an iterative loop of five sustained and transient phases: intention maintenance before target detection (TD), TD, intention maintenance after TD, action, and switching, the latter representing the activation of a new intention in mind. The fMRI analyses revealed continuous engagement of a top-down fronto-parietal network throughout the entire task, likely subserving goal maintenance in mind. In addition, a shift was observed from a perceptual (occipital) system while searching for places to go, to a mnemonic (temporo-parietal, fronto-hippocampal) system for remembering what actions to perform after TD. Updating of the top-down fronto-parietal network occurred at both TD and switching, the latter likely also being characterized by frontopolar activity. CONCLUSION/SIGNIFICANCE: Taken together, these findings show how brain systems complementary interact during real-world PM, and support a more complete model of PM that can be applied to naturalistic PM tasks and that we named PROspective MEmory DYnamic (PROMEDY) model because of its dynamics on both multi-phase iteration and the interactions of distinct neurocognitive networks.

Dance Robot LIVE! is a performance recently shown at the Digital Content Expo in Tokyo. The performance features AIST's feminine HRP-4C robot and four humans. The routine was produced by renowned dancer/choreographer SAM-san and the lip-synced song is a Vocaloid version of "Deatta Koro no Yō ni" by Kaori Mochida (Every Little Thing).

The September issue of Nature Neuroscience has an editorial about the use of microfinance for scientific research.

The editorial is a sign of growing interest from the research community toward this strategy, which I and my colleague Giuseppe Riva described in a letter to Science [Gaggioli, A, Riva, G. (2008) Working the Crowd, Science 321, 5895, 1443]

Recently, we have teamed up with the Institute of Physiology of the National Research Council and the Italian Federation of Rare Diseases to develop Open Genius, a crowdfunding platform for research in rare diseases.

We have also created a website (in Italian and English) where you can find updated information about the project.

Open Genius is a not-for-profit initative of the scientific community that partners with like minded entities including academic, philantropic, government funding agencies.

If you want to collaborate or propose a partnership you can write us to:

info(at)opengenius.org